Compounds <b>19</b> and <b>23</b> also played roles in controlling the onset of epilepsy in EEG, modulating levels of GABA aminotransferase (GABA-AT)/gamma-aminobutyric acid type A receptor (GABA<sub>AR</sub>), interacting with active sites of GABA-AT and GABA<sub>AR</sub> obtained from docking simulation methods. The gene discussed is ABAT; the disease is epilepsy.