The retinal microvasculature was evaluated using digital nonmydriatic fundus photography, the renal microvascular damage through the urinary albumin-to-creatinine ratio (ACR), and the peripheral vasculopathy by the augmentation index (AIx).<h4>Results</h4>Sixty-seven participants were included (22 controls, 24 with prediabetes, 21 with DM; aged: 55.9 ± 9.4 years). The gene discussed is ALB; the disease is vascular disorder.