CHEK1 and metastatic malignant neoplasm in the lymph nodes: <i>Results</i>: In AD, high CHEK1 expression significantly correlated with advanced T stage (<i>p</i> < 0.001), lymph node metastasis (<i>p</i> = 0.025), younger age (<i>p</i> = 0.017), and shorter OS (<i>p</i> = 0.025).