CD274 and neoplasm: We also used PCR and Sanger sequencing to investigate the prevalence of DNA from OtHV-1.<h4>Results</h4>Bioinformatic analyses identified shared somatic variants and DNA copy number aberrations in UGC tumor samples, including recurrent exonic single-nucleotide variants in <i>CD274/PD-L1</i>, and recurrent copy number gains in <i>CD274/PD-L1</i>, <i>TNFRSF14</i>, <i>CD200</i>, <i>CDK4</i>, and <i>PLCG2</i>.