Spatially, PD-1<sup>-</sup>CD103<sup>+</sup>CD8<sup>+</sup> T<sub>RM</sub> cells exhibited increased interactions with tumor cells, whereas PD-1<sup>+</sup>CD103<sup>+</sup>CD8<sup>+</sup> T<sub>RM</sub> cells showed reduced engagement. The gene discussed is ITGAE; the disease is neoplasm.