Notch-signaling is implicated in tumorigenesis as well as Notch-associated long non-coding RNAs (lncRNAs) small nucleolar RNA host gene3 (SNHG3) and leukemia-associated non-coding IGF1R activator RNA 1 (LUNAR1) are highly expressed in various malignant tissues including colorectal cancer (CRC). This evidence concerns the gene LUNAR1 and colorectal carcinoma.