<h4>Objective</h4>To compare the prognostic value between the C-reactive protein-albumin-lymphocyte index (CALLY) and traditional inflammatory markers [including the neutrophil-to-lymphocyte ratio (NLR), the lymphocyte-to-monocyte ratio (LMR), and the platelet-to-lymphocyte ratio (PLR)] after radical resection of colorectal cancer (CRC).<h4>Methods</h4>A total of 152 CRC patients who underwent radical resection in Baotou Central Hospital from January 2016 to December 2019 were selected and studied retrospectively. The gene discussed is ALB; the disease is colorectal carcinoma.