In multivariate analysis, eight variables were independently associated with SMI: age (OR = 1.05, <i>P</i> = 0.001), BMI (OR = 1.10, <i>P</i> = 0.006), diabetes duration (OR = 1.06, <i>P</i> = 0.004), insulin use (OR = 1.72, <i>P</i> = 0.015), SD of glucose (OR = 3.11, <i>P</i> < 0.001), systolic blood pressure (OR = 1.02, <i>P</i> = 0.038), hs-CRP (OR = 1.08, <i>P</i> = 0.009), and eGFR (OR = 0.97, <i>P</i> = 0.003). This evidence concerns the gene INS and diabetes mellitus.