Early liver dysfunction markers strongly predicted worse outcomes: elevated bilirubin nearly doubled mortality risk (HR 1.975, 95%CI 1.100-3.545, p=0.023), and decreased prothrombin activity tripled it (HR 3.055, 95%CI 1.839-5.075, p<0.001).<h4>Conclusions</h4>While the Pringle maneuver extends operative time and intensive care unit stay, it demonstrates a protective effect on survival. This evidence concerns the gene F2 and Decreased liver function.