<h4>Objectives</h4>This study aimed to investigate the expression of programmed cell death protein 1 (PD-1) and lymphocyte-activation gene 3 (LAG-3) on CD4<sup>+</sup> and CD8<sup>+</sup> T cells in children with asthma and their relationship with Th2-associated inflammatory cytokines (IL-4, IL-5, and IL-13). Here, LAG3 is linked to asthma.