During the 12-month follow-up after PCI, CVEs included: mortality (n = 10; GG = 2, GA+AA = 8), stent thrombosis (n = 5; GG = 0, GA+AA = 5), recurrent myocardial infarction (n = 9; GG = 1, GA+AA = 8), ischemia-related hospitalizations (n = 17; GG = 1, GA+AA = 16), and cerebrovascular accidents (n = 3; GG = 0, GA+AA = 3).<h4>Conclusion</h4>Individuals carrying one or two non-functional CYP2C19*2 (rs4244285) alleles - GA and AA genotypes classified as intermediate and poor metabolizers, respectively- - showed a significant association with CVEs. The gene discussed is CYP2C19; the disease is ischemia.