MAPT and supranuclear palsy, progressive, 1: However, the value of sequential [<sup>18</sup>F]PI-2620 imaging for tracking tau accumulation during the disease course has not yet been investigated.<h4>Methods</h4>Twenty-three PSP patients underwent two [<sup>18</sup>F]PI-2620 PET scans (interval: 21.4 ± 4.3 months) and were compared to cross-sectional data from 25 healthy controls.