LRRK2 and Parkinson disease: All analyses were adjusted for biological sex and were exploratory.<h4>Results</h4>The median age at onset (AAO) of LRRK2-PD was 5 years younger in the North African (hazard ratio [HR] = 1.48, 95% confidence interval [CI] = 1.18-1.86, p = 7.0 × 10<sup>-4</sup>) compared with the European ancestry group.