The aim of this study was to investigate the expression of a potential novel therapeutic target and its clinical correlation in sarcomas, namely urokinase plasminogen activator receptor-associated protein (uPARAP/Endo180/CD280).<h4>Materials and methods</h4>We evaluated uPARAP expression in various sarcoma subtypes and in normal tissues using 12 tissue microarrays. Here, MRC2 is linked to sarcoma.