In a separate cohort of 25 GBM-CAM tumours grown under normoxic conditioning, the correlation of glucose metabolism was assessed using [<sup>18</sup>F]FDG-PET on E12 followed by lactate MRS on E13 (n = 8).<h4>Results</h4>Normoxia- and hypoxia-conditioned tumour-bearing CAMs exhibited vascular remodelling and significant upregulation of VEGFA and ADM compared to cultured cells. This evidence concerns the gene ADM and neoplasm.