However, the prognostic role of TF and the related proteins in endometrial cancer is yet to be clarified and was systematically investigated in this study.<h4>Materials and methods</h4>The expression profiles of membrane/cytoplasmic TF, nuclear/cytoplasmic phospho-TF (p-TF), PAR-1, PAR-2, VEGF as well as CD8, a marker for cytotoxic T cells, in tumors from 229 patients with endometrial carcinoma were immunohistochemically evaluated and correlated with clinicopathologic parameters and patient survival. This evidence concerns the gene CD8A and endometrial cancer.