HMGB1 and Parkinson disease: Although miR-141-3p is downregulated in the peripheral blood serum of Parkinson's disease (PD) patients, its potential relationship with HMGB1 remains unclear.<h4>Methods</h4>TargetScan software and dual-luciferase reporter gene assays predicted that miR-141-3p binds to the 3'-UTR of HMGB1 mRNA.