This study investigates the effects of <i>Taenia solium</i> metacestode-derived thioredoxin peroxidase (TPx) protein on regulatory T (Treg) cells and T helper 17 (Th17) cell differentiation, as well as its correlation with signaling pathways in human Jurkat T lymphocytes exposed to TPx for varying durations, to provide a scientific basis for further studying the immune pathogenesis and clinical treatment of cysticercosis.<h4>Methods</h4>TPx protein from the excretory-secretory antigens of <i>T. This evidence concerns the gene TPO and cysticercosis.