The NRI and IDI of the combined model incorporating serum lncRNA H19, miR-675, and PPARα protein levels were statistically superior to lipid-based models (<i>P</i> < 0.05).<h4>Conclusions</h4>Serum lncRNA H19 and miR-675 were not associated with macrosomia risk. Here, PPARA is linked to Large for gestational age.