The most common mutation was BRAF<sup>V600E</sup> present in 36.94%, followed by the mutation in FGFR1, reported in 1.18% of cases.<h4>Conclusion</h4>BRAF<sup>V600E</sup> mutation was the most common alteration observed in gangliogliomas, whereas mutations in other genes, such as FGFR1, H3K27M, KRAS, IDH1, and RAF1, were rare. This evidence concerns the gene RAF1 and ganglioglioma.