INS and type 2 diabetes mellitus: thetaiotaomicron</i> to T2DM rats led to significant reductions in body weight (BW) (8%), Body Mass Index (BMI) (21%), Lee index (10%), fasting blood glucose (FBG) (16%), insulin (46%), homeostatic model assessment of IR (HOMA-IR) (56%), triglycerides (TG) (34%), total cholesterol (TC) (29%), and low-density lipoprotein cholesterol (25%) (all P ≤ 0.012).