During subsequent follow-up, the patient remained on low-dose glucocorticoids without any significant adverse effects.<h4>Conclusion</h4>Adult anti-NXP-2 antibody-positive dermatomyositis complicated by rhabdomyolysis has been documented only sporadically; its co-occurrence is estimated at <1%, placing it in the ultra-rare category. Here, MORC3 is linked to dermatomyositis.