Compared to uncomplicated appendicitis, complicated appendicitis showed statistically significantly elevated levels in interleukin 6 (IL-6) (p < 0.001), hepatocyte growth factor (HGF) (p = 0.003), and monocyte chemoattractant protein 1 (MCP-1) (p < 0.001). This evidence concerns the gene HGF and appendicitis.