Aberrant STAT3 activation and overproduction of IL-21 in systemic lupus erythematosus: role of miR-155 and miR-21 in target genes &lt;i&gt;SOCS1, PTEN&lt;/i&gt; and &lt;i&gt;PIAS3&lt;/i&gt;. The gene discussed is SOCS1; the disease is systemic lupus erythematosus.