At 1 hour and 24 hours post-infection, we assessed inflammatory cytokine expression (IL-1β, CCL2, IL-8), tight junction protein levels (occludin, ZO-1) and bacterial survival.<h4>Results</h4>HCA modulated inflammation in pathogen-specific manner: IL-1β induction by <i>S. The gene discussed is TJP1; the disease is infection.