MLKL and diabetes mellitus: To investigate its role in disease progression, mice whose liver parenchymal cells (LPCs) no longer expressed MLKL (Mlkl<sup>LPC-KO</sup>) were compared to their control counterparts (Mlkl<sup>fl/fl</sup>) using an experimental model combining diabetes induction and a high-fat high-sugar diet (HFHSD) for 4, 8, or 12 weeks.