This study aims to assess the value of semi-automatic CMR-derived biplane functional parameters in patients with cardiac light chain (AL) and transthyretin (ATTR) amyloidosis or hypertrophic cardiomyopathy (HCM).<h4>Methods</h4>This retrospective, multi-center, multi-vendor study included patients with a diagnosis of HCM or cardiac AL/ATTR amyloidosis. Here, TTR is linked to hypertrophic cardiomyopathy.