Anastomotic healing (AH) was tested in a mouse model using wild-type (WT), AhR<sup>-/-</sup>, Villin<sup>Cre</sup>Ahr<sup>fl/fl</sup>, and interleukin (IL)-22 drug-targeting to evaluate the role of AhR and IL-22 in AL.<h4>Results</h4>Fifty-two of the 388 patients with available preoperative fecal samples were matched for AH/AL occurrence (AL, n = 19; AH, n = 33). The gene discussed is AHR; the disease is axial length measurement.