A longitudinal study was carried out using LNCaP tumor-bearing mice imaged with [<sup>43</sup>Sc]Sc-PSMA-617 prior to receiving a therapeutic dose of [<sup>47</sup>Sc]Sc-PSMA-617.<h4>Results</h4><sup>43</sup>Sc and <sup>47</sup>Sc were incorporated into PSMA-617 at radiochemical yields of >99%. Here, FOLH1 is linked to neoplasm.