JAK1 and obstructive sleep apnea syndrome: <h4>Background</h4>Chronic obstructive sleep apnea (OSA) drives systemic inflammation; the role of the JAK1-STAT1 pathway is unclear.<h4>Objective</h4>To elucidate JAK1-STAT1 involvement in OSA-related inflammation using a chronic intermittent hypoxia (CIH) model.<h4>Methods</h4>Sprague-Dawley rats underwent 8-week CIH (FiO2 cycling 5-21%, 8h/day) or normoxia (Sham).