No significance could be detected comparing SI histogram parameters between oligodendrogliomas and diffuse astrocytomas.<h4>Conclusion</h4>Our investigation demonstrates the potential of T2 SI Entropy in distinguishing grade 1 from grade 2 gliomas and in reflecting the proliferative activity denoted by Ki-67 expression, therefore being a promising HA feature for assessing tumor heterogeneity. This evidence concerns the gene MKI67 and glioma.