However, its prognostic significance in patients with active cancer (AC) and acute ischemic stroke (AIS) remains unclear.<h4>Objectives</h4>This study evaluates the association between plasma TF activity and outcome in patients with AC and AIS.<h4>Methods</h4>We analyzed data from the SCAN study, a prospective, multicenter, observational study conducted in Japan. The gene discussed is TF; the disease is cancer.