We performed NanoString gene expression profiling of AITL patient samples to identify AITL cases that are relevant to <i>Roquin<sup>san/+</sup></i> mouse model.<h4>Results</h4>DE Tfh cells expressed higher levels of Ki-67 and enhancer of zeste homolog 2 (EZH2) and proliferated more rapidly compared to other Tfh cells in an IL-18 and EZH2 dependent manner. Here, MKI67 is linked to angioimmunoblastic T-cell lymphoma.