This study evaluates the impact of PSMA-PET on recurrent post-prostatectomy patients treated with radiotherapy (RT) ± hormonal therapy (HT).<h4>Materials and methods</h4>In a prospective, observational study (2016-2020), 103 hormone-sensitive post-prostatectomy pN0-pNx PCa patients with proven BCR were analyzed. This evidence concerns the gene BCR and posterior cortical atrophy.