After cross validation with the MI/HF dataset, six robust biomarkers (<i>TMEM43</i>, <i>C1orf174</i>, <i>L3MBTL4</i>, <i>OR52N4</i>, <i>SLC25A20</i>, <i>MISP3</i>) were screened. This evidence concerns the gene MISP3 and hydrops fetalis.