Pan-macrophage (CD14, CD68), HBC-enriched (FOLR2, VSIG4), M1 (CD86), and M2 (CD163, MRC1) markers were assessed by RT-qPCR and quantitative immunohistochemistry.<h4>Results</h4>In both non-GDM and GDM placentae, all markers, except CD86 were detected, supporting an M2-like HBC phenotype. The gene discussed is CD68; the disease is gestational diabetes.