This study aimed to test the efficacy of human umbilical mesenchymal stem cell-derived mitochondrial transplantation (Mito-T) on preeclampsia (PE).<h4>Methods</h4>PE was induced in Sprague-Dawley pregnant rats by infusing angiotensin II (Ang II) starting on gestation day 8 (GD 8). The gene discussed is AGT; the disease is preeclampsia.