Single-cell transcriptomic analysis showed that 10 of the 12 selected RMEs (DKC1, METTL1, NAT10, TRMT1, RPUSD1, PUS1, WDR4, TRMU, ADAT2, GTPBP3) exhibited higher expression in tumor-infiltrating cells compared with adjacent normal tissues. This evidence concerns the gene PUS1 and neoplasm.