LEP and type 2 diabetes mellitus: Moreover, leptin protein levels showed a positive correlation with increased BMI and TG, while sOb-R protein levels showed a positive correlation with increased BMI, FBG, and TG levels.<h4>Conclusion</h4>The <i>LEPR rs1137101 A/G</i> polymorphism, together with elevated leptin, and decreased sOb-R protein levels, may increase susceptibility to T2D in the Gujarat population.