Concurrently, the infection also increased the numbers of CD3<sup>+</sup> T cells, including CD4<sup>+</sup> and CD8<sup>+</sup> T, CD4<sup>+</sup> Tcm, CD4<sup>+</sup> Tem, CD4<sup>+</sup> tissue resident memory T (Trm), CD8<sup>+</sup> Tcm, CD8<sup>+</sup> Tem, CD8<sup>+</sup> Trm and CD8<sup>+</sup> SLEC in tumor tissues. The gene discussed is CD4; the disease is infection.