Dozens of genes and transcripts are found in the 15q11-q13 region, and may play a role in PWS, specifically paternally expressed <i>SNURF-SNRPN</i> and <i>MAGEL2</i> genes, while AS is due to the maternally expressed <i>UBE3A</i> gene. This evidence concerns the gene UBE3A and Prader-Willi syndrome.