ALK and adenocarcinoma: <b>Results</b>: ALK-positive patients were significantly associated with female gender (<i>p</i> = 0.002), non-smoking status (<i>p</i> = 0.001), adenocarcinoma histology (<i>p</i> = 0.001), and a higher incidence of brain metastases (<i>p</i> = 0.001).