We investigated the prognostic significance of preoperative lactate dehydrogenase (LDH) and two LDH-based indices, the LDH-to-lymphocyte ratio (LLR) and LDH-to-albumin ratio (LAR), in patients undergoing curative resection for GC.<h4>Methods</h4>We retrospectively reviewed the medical records of 225 consecutive patients with GC who underwent R0 surgical resection. Here, ALB is linked to gastric cancer.