Recurrence occurred in 50.0% of patients in the MOG-Ab (+) group within 1 year of discharge follow-up, compared to only 12.50% in the MOG-Ab (-) group (χ<i>2</i> = 3.938, <i>P</i> = 0.047).<h4>Conclusion</h4>For patients with anti-NMDAR encephalitis presenting with headaches, if there is a significant increase in CSF-WBC count, coupled with abnormal MRI signals in the leptomeninges or cortex, it is recommended to test for MOG antibodies. The gene discussed is MOG; the disease is Headache.