Despite this, and schizophrenia's association with 5-hydroxytryptamine (serotonin) system dysfunction, <i>HTR5A-AS1</i>, a long noncoding RNA (lncRNA) antisense to the serotonin receptor (HTR, 5-hydroxytryptamine receptor) gene <i>HTR5A</i>, remains virtually unstudied. Here, HTR5A is linked to schizophrenia.