CD4 and AIDS: The comparison of the discriminative capacity of the Dat'AIDS score with the VACS indices was performed.<h4>Results</h4>A total of 1330 participants (75.5% male, median age: 73.7 years, median time since HIV diagnosis: 21.7 years, median time under combination antiretroviral therapy (cART): 19.9 years, median CD4 cell count: 553 cells/μL, HIV-1 RNA ≤50 copies/mL: 88.7%) were included.