Compared with controls, patients with RML were older and more likely to have neurological comorbidities, recent falls, impaired consciousness, infection, effective serum osmolality >320 mOsm/kg, leukocytosis, higher C-reactive protein, elevated creatinine, acute kidney injury, markedly raised myoglobin, and elevated troponin I. RML was associated with a longer hospital stay, higher costs, a higher in-hospital mortality (11.1 vs 0.67%), and a higher rate of the composite poor outcome (16.7 vs 1.11%). This evidence concerns the gene MB and infection.