In multivariable linear regression, systolic blood pressure (SBP), tumor necrosis factor-alpha (TNF-α), and body fat percentage independently predicted STOX1 (Y_STOX1 = 2.569 - 0.110 × SBP - 0.272 × TNF-α - 0.106 × body fat %; <i>R</i> = 0.37, <i>R</i> <sup>2</sup> = 0.13).<h4>Discussion</h4>During OGTT, hyperglycemia suppressed circulating STOX1, suggesting glucose-dependent regulation of its secretion/release. The gene discussed is TNF; the disease is Hyperglycemia.