This follow-up study aimed to assess CAMKK2/TF/TFRC protein levels in hippocampal tissues - an early site of AD pathology - and examine their relationship with tau (MAPT) aggregation in AD, Parkinson's disease (PD), and frontotemporal dementia (FTD).<h4>Methods</h4>Postmortem hippocampal tissues from 29 CN individuals and patients diagnosed with AD/FTD/PD (N = 73/7/9 respectively) were analyzed. The gene discussed is TFRC; the disease is frontotemporal dementia.