Kruskal-Wallis or one-way ANOVA with post hoc tests (Holm-Sidak and Dunn's tests), as well as univariate/multivariate linear regression analyses, were used to determine the correlation between GDF-15 and coagulation parameters in male patients with CAD.<h4>Results</h4>Compared to controls, patients with acute myocardial infarction (AMI) and stable angina (SA) showed significantly higher levels of GDF-15 (<i>p</i> < 0.05). The gene discussed is GDF15; the disease is angina pectoris.