Multivariate linear regression revealed that GDF-15 levels were positively associated with activated partial thromboplastin time (APTT) in patients with CAD (β = 0.109, <i>p</i> = 0.024), and inversely associated with antithrombin III (AT3) (β = -0.113, <i>p</i> = 0.028) in an adjusted multivariate regression model. This evidence concerns the gene GDF15 and coronary artery disorder.